In a recent publication Travis Timmerman has claimed that sometimes it is morally permissible to not prevent something bad from happening, even if it is in one’s power to do so without sacrificing anything nearly as important.1 To defend his point, he has proposed a thought experiment and based his claims on putative common-sense morality intuitions. To aid in the subsequent discussion, Timmerman’s case is reproduced as follows.

Peter Achinstein has argued at length and on many occasions that the view according to which evidential support is defined in terms of probability-raising faces serious counterexamples and, hence, should be abandoned. Proponents of the positive probabilistic relevance view have remained unconvinced. The debate seems to be in a deadlock. This paper is an attempt to move the debate forward and revisit some of the central claims within this debate. My conclusion here will be that while Achinstein may be right (...) that his counterexamples undermine probabilistic relevance views of what it is for e to be evidence that h, there is still room for a defence of a related probabilistic view about an increase in being supported, according to which, if p > p, then h is more supported given e than it is without e. My argument relies crucially on an insight from recent work on the linguistics of gradable adjectives. (shrink)

This paper elaborates a new solution to the lottery paradox, according to which the paradox arises only when we lump together two distinct states of being confident that p under one general label of ‘belief that p’. The two-state conjecture is defended on the basis of some recent work on gradable adjectives. The conjecture is supported by independent considerations from the impossibility of constructing the lottery paradox both for risk-tolerating states such as being afraid, hoping or hypothesizing, and for risk-averse, (...) certainty-like states. The new proposal is compared to views within the increasingly popular debate opposing dualists to reductionists with respect to the relation between belief and degrees of belief. (shrink)

According to recently popular pragmatist views it may be rational for one to believe p when one’s evidence doesn’t favour p over not-p. This may happen according to pragmatists in situations where one can gain something practically important out of believing p. In this paper I argue that given some independently plausible assumptions about the argumentative nature of philosophy and the irrelevance of bribes for good arguments, pragmatism leads to a contradiction.

I maintain that among the main views concerning the central questions of epistemology (in particular, the question of justified belief) are evidentialism, (Pyrrhonian) scepticism and fideism. In this paper, I first present the arguments in favour of a form of evidentialism, according to which no false belief can be epistemically justified on the basis of evidence. Second, I consider the historical emergence of evidentialism during the period of the early Enlightenment. In particular, I explore the disagreement between Pierre Bayle and (...) Jean-Pierre de Crousaz, which demonstrates the emergence of the modern opposition between evidentialism and fideism. (shrink)

In this article I focus on some unduly neglected common-sense considerations supporting the view that one's evidence is the propositions that one knows. I reply to two recent objections to these considerations.

According to the good reasoning view of normative reasons, p is a reason to F, just in case p is a premise of a good pattern of reasoning. This article presents two counterexamples to the most promising version of the good reasoning view.

In this paper, I argue against recent versions of justification norms of action and practical deliberation . I demonstrate that these norms yield unacceptable results in deception cases. However, a further modification of justification norms in the light of these results appears to be ad hoc. Hence, I claim, we should reject justification norms of action and practical deliberation.

The dominant theory of judgment in 1870 was one or other variety of combination theory: the act of judgment is an act of combining concepts or ideas in the mind of the judging subject. In the decades to follow a succession of alternative theories arose to address defects in the combination theory, starting with Bolzano’s theory of propositions in themselves, Brentano’s theory of judgment as affirmation or denial of existence, theories distinguishing judgment act from judgment content advanced by Brentano’s students (...) Twardowski, Husserl and Meinong, and finally, Adolf Reinach’s addition of a linguistic dimension to the Brentano-Husserlian theory of judgment – an account of judgments as ways of doing things with words in what Reinach called ‘social acts’. (shrink)

According to the knowledge view of evidence notoriously defended by Timothy Williamson (2000), for any subject, her evidence consists of all and only her propositional knowledge (E=K). Many have found (E=K) implausible. However, few have offered arguments against Williamson’s positive case for (E=K). In this paper, I propose an argument against Williamson’s positive case in favour of (E=K). Central to my argument is the possibility of the knowledge of necessary truths. I also draw some more general conclusions concerning theorizing about (...) evidence. (shrink)

The aim of the article is to outline an interpretation of the philosophical understanding of the concept of the good in pre-Platonic thought. The interpretation is based on those fragments only in which the concept actually appears. As a result of the adopted assumption, the ideas of the first philosophers, i.e. Thales, Anaximander and Anaximenes, were outside the scope of the investigation, as well as those of Xenophanes, Eleatics, Empedocles, Anaxagoras and Leucippus. In the case of the first philosophical systems (...) of the pre-Platonic philosophy one notices a connection between the good and the One. It can also be found that understanding of the ‘the Best’ is depended on, and results from, ‘the good’. This is true also in Heraclitus, though, at the same time, he introduces an significant reversal in this respect, for he abolishes the absolute difference between the good and evil, and turns it to a subjective relation. The good has no ontological basis in the Democritus’ system as well, though the good’s connection with truth, accessible for every human being, allows to interpret him as arguing for an objectivistic conception of the good. The objectivity of good has subsequently been denied by the Sophists. (shrink)

The aim of the present paper is to show how Plato suggested demarcating between knowledge and other kinds of human intellectual activities. The article proposes to distinguish between two ways of such a demarcation. The first, called `the external demarcation', takes place when one differentiates between knowledge and non-knowledge, the rational and non-rational or the reasonable and non-reasonable. The second, called `internal', marks the difference within knowledge itself and could be illustrated by the difference between the so called hard and (...) soft sciences. The analyses lead tothe following conclusions. Plato refers to the whole of human intellectual activity as doxa, which is divided into two spheres. The first of them is knowledge proper whose criterion is phronesis. Three other kinds of doxa are derived from knowledge proper: 1) the traditional peri phuseos investigation (called also sophia); 2) popular doxai concerning virtues; 3) wisdom of the antilogikoi. The difference represents the external demarcation. There may be, however, a difference in the scope of knowledge proper (the internal demarcation). If the peri phuseos investigators were able to explain the field of values, the result of their investigation could be acknowledged as knowledge, although it would still be characterized as inferior due to its being based on senses. What is interesting about knowledge proper is that it is not firm and reliable but only hypothetical. It does not determine the skeptical reading of the Phaedo but it indicates that Plato has just begun his own philosophical project (which is still in progress) and the knowledge presented in the dialogue is his first positive suggestion how to solve the problem of demarcation. (shrink)

According to one line of thought only propositions can be part of one’s evidence, since only propositions can serve the central functions of our ordinary concept of evidence. Ram Neta has challenged this argument. In this paper I respond to Neta’s challenge.

The aim of this paper is to show that the account of objective truth taken for granted by logicians at least since the publication in 1933 of Tarski’s “The Concept of Truth in Formalized Languages” arose out of a tradition of philosophical thinking initiated by Bolzano and Brentano. The paper shows more specifically that certain investigations of states of affairs and other objectual correlates of judging acts, investigations carried out by Austrian and Polish philosophers around the turn of the century, (...) formed part of the background of views that led to standard current accounts of the objectivity of truth. It thus lends support to speculations on the role of Brentano and his heirs in contemporary logical philosophy advanced by Jan Wolenski in his masterpiece of 1989 on the Logic and philosophy in the Lvov-Warsaw School. (shrink)

A common assumption in contemporary debates about normative reasons is that ‘subjective’ and ‘possessed’ are two names for the same sort of reason. This paper challenges that assumption. Given our cognitive limitations, it is unsurprising that normative reasons that derive from what we know and reasons that we are in a position to use in our deliberation are not always one and the same.

Series of articles about Plato's dialogue "Theaetetus".

In this paper I examine Williamson’s (2000) claim that all evidence is propositional. I propose to reject this claim. I give two objections to two premises of Williamson’s argument. The first is a critique of Williamson’s claim that we choose between hypotheses on the basis of our evidence. The second objection is that Williamson’s claim that evidence is an explanandum of an hypothesis leads to counter-intuitive consequences and thus is not central to what evidence is, at least on an ordinary (...) understanding. (shrink)

The dominant theory of judgment in 1870 was one or other variety of combination theory: the act of judgment is an act of combining concepts or ideas in the mind of the judging subject. In the decades to follow a succession of alternative theories arose to address defects in the combination theory, starting with Bolzano’s theory of propositions in themselves, Brentano’s theory of judgment as affirmation or denial of existence, theories distinguishing judgment act from judgment content advanced by Brentano’s students (...) Twardowski, Husserl and Meinong, and finally, Adolf Reinach’s addition of a linguistic dimension to the Brentano-Husserlian theory of judgment – an account of judgments as ways of doing things with words in what Reinach called ‘social acts’. (shrink)

The aim of the present article is to accomplish two things. The first is to show that given some further plausible assumptions, existing challenges to the indispensability of knowledge in causal explanation of action fail. The second is to elaborate an overlooked and distinct argument in favor of the causal efficacy of knowledge. In short, even if knowledge were dispensable in causal explanation of action, it is still indispensable in causal explanation of other mental attitudes and, in particular, some reactive (...) attitudes and factive emotions. Taking into account this sort of causal efficacy in determining which mental states are genuine mental states opens up new perspectives for defending the view that knowledge is the most general factive and genuine mental state. (shrink)

According to a widely held view epistemic justification is a normative notion. According to another widely held assumption, epistemic justification comes in degrees. Given that gradability requires a context-sensitivity that normativity seems to lack, these two assumptions stand in tension. Giving up the assumption of gradability of justification represents a lesser theoretical cost.

The dominant theory of judgment in 1870 was one or other variety of combination theory: the act of judgment is an act of combining concepts or ideas in the mind of the judging subject. In the decades to follow a succession of alternative theories arose to address defects in the combination theory, starting with Bolzano’s theory of propositions in themselves, Brentano’s theory of judgment as affirmation or denial of existence, theories distinguishing judgment act from judgment content advanced by Brentano’s students (...) Twardowski, Husserl and Meinong, and finally, Adolf Reinach’s addition of a linguistic dimension to the Brentano-Husserlian theory of judgment – an account of judgments as ways of doing things with words in what Reinach called ‘social acts’. (shrink)

In this paper I discuss the role that knowledge plays with regard to rational action. It has been recently argued that knowledge determines appropriate action. I examine this proposal, consider objections against it, and finally propose a defense of it.

Series of articles about Plato's dialogue "Theaetetus".

The paper investigates the issue of historicity of existence and self-understanding within Gadamer’s philosophical hermeneutics. The purpose of the paper is to answer the question of how the author of Truth and method argues and interprets the unity of existence in the context of recognizing historicity as the fundamental characteristics of human being and the world. The paper shows that the historicity excludes the possibility of basing this unity on an absolute metaphysical foundation or on a reflective self-consciousness of transcendental (...) subjectivity. On the ground of philosophical hermeneutics, being-one of a human has the character of historical continuity, constituted in the process of incessant, interpretive transcending and uniting oneself. The paper shows what roles the inherited tradition and community in which one lives play in this process. Furthermore, the paper points out that for proper understanding of Gadamer’s interpretation of the unity of existence, it is necessary to take into account two issues: firstly, its departure from the concept of empty time, which is a stream of the past, present and future moments of the “Now”, in favour of ful-filled time and secondly, how general-individual relations are interpreted in philosophical hermeneutics. (shrink)

The article discusses the nature and significance of metaphilosophical knowledge on the ground of Heidegger’s fundamental ontology. The purpose of the article is to show metaphilosophical knowledge as an essential and immanent factor of philosophical reflection. The above mentioned goal is achieved by presenting connection, occurring within the fundamental ontology, between this knowledge and theoretical philosophical reflection, both in its descriptive (defining being of philosophy) and normative (indicating how philosophical reflection should be carried out) dimension. The descriptive dimension of the (...) connection indicates a circular nature of the interactions between metaphilosophical and theoretical aspects of philosophy. The theoretical reflection on specific phenomena is, at the same time, a determination of being of the philosophy; whereas the metaphilosophical knowledge, arising from the theoretical reflection, determines character and direction of further considerations. Furthermore, the normative dimension implies that philosophical considerations should take into account this connection and deliberately practice it through systematic metaphilosophical reflection. As the source of the connection between metaphilosophical knowledge and theoretical reflection, the article indicates Heidegger’s concept of philosophy, according to which philosophy is a way of being of Dasein, consisting of ontological, conceptual interpretation of being of beings and reflecting the structures of Dasein’s existence and its pre-ontological understanding of being. -/- Keywords: fundamental ontology, metaphilosophy, philosophical reflection, grounding of philosophy, Dasein, understanding of being. (shrink)

Teachers encountered numerous challenges posed by the COVID-19 outbreak. Herewith, this study aimed to determine the challenges encountered by Filipino teachers in the new normal and their coping mechanisms. This study employed a qualitative inquiry to determine the challenges encountered and coping mechanisms employed by teachers amid modular instruction, involving 10 teachers from five secondary schools in the Philippines who participated voluntarily. Data were gathered through a written narrative from each participant and were analyzed thematically. Themed findings showed that these (...) teachers are greatly challenged in terms of learning quality transfer, module distribution and retrieval, students’ difficulties in following instruction, power disruption, internet connection, and health risks posed by the pandemic. Nevertheless, these teachers dealt with these difficulties by employing their own coping techniques. Teaching can be challenging and frustrating, especially in these difficult times, but as these teachers demonstrated, everything is possible. Hence, educators must be ready for any situation that may arise. This situation is unlikely to get better anytime soon; instead, teachers will need to adjust to and accept this reality. (shrink)

Machine learning algorithms may radically improve our ability to diagnose and treat disease. For moral, legal, and scientific reasons, it is essential that doctors and patients be able to understand and explain the predictions of these models. Scalable, customisable, and ethical solutions can be achieved by working together with relevant stakeholders, including patients, data scientists, and policy makers.

According to proponents of the extended mind, bio-external resources, such as a notebook or a smartphone, are candidate parts of the cognitive and mental machinery that realises cognitive states and processes. The present chapter discusses three areas of ethical concern associated with the extended mind, namely mental privacy, mental manipulation, and agency. We also examine the ethics of the extended mind from the standpoint of three general normative frameworks, namely, consequentialism, deontology, and virtue ethics.

Despite the ubiquity of inner speech in our mental lives, methods for objectively assessing inner speech capacities remain underdeveloped. The most common means of assessing inner speech is to present participants with tasks requiring them to silently judge whether two words rhyme. We developed a version of this task to assess the inner speech of a population of patients with aphasia and corresponding language production deficits. As expected, patients’ performance on the silent rhyming task was severely impaired relative to controls. (...) More surprisingly, however, patients’ performance on this task did not correlate with their performance on a variety of other standard tests of overt language abilities. In particular, patients who were generally unimpaired in their abilities to overtly name objects during confrontation naming tasks, and who could reliably judge when two words spoken to them rhymed, were still severely impaired (relative to controls) at completing the silent rhyme task. This seems to suggest that inner speech was more severely impaired in these patients than outer speech. However, these results should also cause us to critically reflect on the relation between inner speech and silent rhyme judgments more generally. (shrink)

In the exploratory study reported here, we tested the efficacy of an intervention designed to train teenagers with Möbius syndrome (MS) to increase the use of alternative communication strategies (e.g., gestures) to compensate for their lack of facial expressivity. Specifically, we expected the intervention to increase the level of rapport experienced in social interactions by our participants. In addition, we aimed to identify the mechanisms responsible for any such increase in rapport. In the study, five teenagers with MS interacted with (...) three naïve participants without MS before the intervention, and with three different naïve participants without MS after the intervention. Rapport was assessed by self-report and by behavioral coders who rated videos of the interactions. Individual non-verbal behavior was assessed via behavioral coders, whereas verbal behavior was automatically extracted from the sound files. Alignment was assessed using cross recurrence quantification analysis and mixed-effects models. The results showed that observer-coded rapport was greater after the intervention, whereas self-reported rapport did not change significantly. Observer-coded gesture and expressivity increased in participants with and without MS, whereas overall linguistic alignment decreased. Fidgeting and repetitiveness of verbal behavior also decreased in both groups. In sum, the intervention may impact non-verbal and verbal behavior in participants with and without MS, increasing rapport as well as overall gesturing, while decreasing alignment. (shrink)

Since its publication, the Psychopathic Personality Inventory and its revision (Lilien- feld & Andrews, 1996; Lilienfeld & Widows, 2005) have become increasingly popular such that it is now among the most frequently used self-report inventories for the assessment of psychopathy. The current meta-analysis examined the relations between the two PPI factors (factor 1: Fearless Dominance; factor 2: Self-Centered Impulsivity), as well as their relations with other validated measures of psychopathy, internalizing and externalizing forms of psychopathology, general personality traits, and antisocial (...) personality disorder symptoms. Across 61 samples reported in 49 publications, we found support for the convergent and criterion validity of both PPI factor 2 and the PPI total score. Much weaker validation was found for PPI factor 1, which manifested limited convergent validity and a pattern of correlations with central criterion variables that was inconsistent with many conceptualizations of psychopathy. (shrink)

Tristan Augusta von Platena jako jedyny utwór biedermeierowskiego poety znalazł się w ścisłym kanonie liryki niemieckiej. Wiersz doczekał się jednak do tej pory niewielu wnikliwych analiz; nadto zarówno starsze, jak i najnowsze propozycje interpretacyjne koncentrowały się głównie na kontekście biograficznym. Artykuł jest próbą poszerzenia istniejącej literatury przedmiotowej o nowe aspekty. Stawia on przede wszystkim pytanie o obecność mitu w strukturze utworu. Szczegółowa analiza formalna oraz rozważania o warstwie filozoficzno-estetycznej wiersza konsekwentnie ukazują indywidualny gest, z jakim autor adaptuje mityczny topos o (...) transgresywnej miłości. W tym kontekście średniowieczny motyw Tristana jawi się w wierszu wzbogacony o antyczny motyw Orfeusza. Owa oryginalna kontaminacja świadczy o antycypacji przez PIatena niemieckiej poezji modernistycznej, szczególnie zaś wskazuje na powinowactwo jego Tristana z Sonetami do Orfeusza Rilkego. (shrink)

Last year saw the 20th anniversary edition of JECP, and in the introduction to the philosophy section of that landmark edition, we posed the question: apart from ethics, what is the role of philosophy ‘at the bedside’? The purpose of this question was not to downplay the significance of ethics to clinical practice. Rather, we raised it as part of a broader argument to the effect that ethical questions – about what we should do in any given situation – are (...) embedded within whole understandings of the situation, inseparable from our beliefs about what is the case, what it is that we feel we can claim to know, as well as the meaning we ascribe to different aspects of the situation or to our perception of it. Philosophy concerns fundamental questions: it is a discipline requiring us to examine the underlying assumptions we bring with us to our thinking about practical problems. Traditional academic philosophers divide their discipline into distinct areas that typically include logic: questions about meaning, truth and validity; ontology: questions about the nature of reality, what exists; epistemology: concerning knowledge; and ethics: how we should live and practice, the nature of value. Any credible attempt to analyse clinical reasoning will require us to think carefully about these types of question and the relationships between them, as they influence our thinking about specific situations and problems. So, the answers to the question we posed, about the role of philosophy at the bedside, are numerous and diverse, and that diversity is illustrated in the contributions to this thematic edition. (shrink)

According to strong pluralism, objects distinct by virtue of their modal properties can coincide. The most common objection towards such view invokes the so-called Grounding Problem according to which the strong pluralist needs to explain what the grounds are for supposed modal differences between the coincidents. As recognized in the literature, the failure to provide an answer to the Grounding Problem critically undermines the plausibility of strong pluralism. Moreover, there are strong reasons to believe that strong pluralists cannot provide an (...) explanation of the Grounding Problem. In this paper, we argue that strong pluralism can be motivated independently of the successful answer to the Grounding Problem. In order to achieve that aim, we provide a haecceitistic interpretation of strong pluralism according to which strong pluralism should be read as a position committed to the existence of primitive individuals, i.e., the individuals that have their criteria of individuation independently of their qualitative profiles. That said, we do not aim at defending haecceitism. Instead, our aim is rather modest: we want to provide a new way for the strong pluralist to supplement his view to make it more watertight. (shrink)

In this paper, we highlight some problems for accounts of disability and enhancement that have not been sufficiently addressed in the literature. The reason, we contend, is that contemporary debates that seek to define, characterise or explain the normative valence of disability and enhancement do not pay sufficient attention to a wide range of cases, and the transition between one state and another. In section one, we provide seven cases that might count as disability or enhancement. We explain why each (...) case might count, and on what basis, and why it is been neglected. Each case is explained as a transition in what we call capacity space. We then argue that no definition of disability or enhancement addresses all of these cases, except for strict welfarist accounts of disability that do not rely on a depiction of any particular capacity. We argue further, however, that this is a serious deficiency of welfarist conceptions of disability. We then address objections to our account. (shrink)

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

The goal of the study is to analyse the relation between students' digital learning and transversal skills, as well as between students' digital learning and virtues. In the correlative study, 73 teachers of Class 12 of general education institutions participated, filling out a questionnaire in the Google Docs environment. As a result of the theoretical analysis, the criteria for digital learning have been identified -access to digital technologies, cooperation, teachers’ digital competence and availability of activities in compliance with cognitive engagement (...) levels. The findings of the correlation analysis show that the availability of activities in compliance with cognitive engagement levels is the most important in the development of transversal skills,while in the inculcation of virtues -cooperation. The access to digital technologies has a statistically significant correlation with both transversal skills and virtues. The teachers’ digital competence promotes digital literacy and such virtues as responsibility and wisdom. The recommendations developed as part of the study include compilation and promotion of the positive experiences of digital learning at the state and local government level; continuous monitoring and feedback analysis of purposeful digital learning and educational quality at school and classroom level; the application of digital learning resources based on the offer of activities in compliance with the students' cognitive engagement levels at the personal level. Keywords:Digital technologies, cooperation, digital competence, cognitive engagement. (shrink)

Although ethics is an essential component of undergraduate medical education, research suggests current medical ethics curricula face considerable challenges in improving students’ ethical reasoning. This paper discusses these challenges and introduces a promising new mode of graduate and professional ethics instruction for overcoming them. We begin by describing common ethics curricula, focusing in particular on established problems with current approaches. Next, we describe a novel method of ethics education and assessment for medical students that we have devised, the Medical Ethics (...) Bowl. Finally, we suggest pedagogical advantages to MEBs when compared to other ethics curricula. (shrink)

Death is a state of the total disappearance of life. Dying is a process of decay of the vital system, which ends with clinical death. In current perspectives there are several approaches to research on death and dying; these are the clinical, the humanistic, the philosophical, the psychological, the anthropological, and the sociological perspective.

This paper presents and critically discusses the “logos approach to quantum mechanics” from the point of view of the current debates concerning the relation between metaphysics and science. Due to its alleged direct connection with quantum formalism, the logos approach presents itself as a better alternative for understanding quantum mechanics than other available views. However, we present metaphysical and methodological difficulties that seem to clearly point to a different conclusion: the logos approach is on an epistemic equal footing among alternative (...) realist approaches to quantum mechanics. (shrink)

This study aims to find out the factors that hinder students in learning Integrated Art Education. A descriptive research design was utilized in the conduct of the study. The researcher prepared a questionnaire with 15 closed-ended- questions that could be answered objectively. The study discovered that the students would learn more when they feel that they belong to a certain group. Interests in a subject also matter, the more you are interested in a particular subject, the more you will learn (...) the material. Parent support marks an impact on the student's interest in learning Arts. Therefore, personal interest in a subject must be given attention and managed properly. Parent's support also plays a vital role in reinforcing the students on what to pursue in order to maintain their motivation. (shrink)

This study aimed to understand the preserved elements of self-identity in persons with moderate to severe dementia attributable to Alzheimer’s disease. A semi-structured interview was developed to explore the narrative self among residents with dementia in a residential care facility and residents without dementia in an independent living setting. The interviews were transcribed verbatim from audio recordings and analyzed for common themes, while being sensitive to possible differences between the groups. The participants with dementia showed evidence of self-reference even though (...) losses in explicit memory were evident. The most noticeable difference between the two groups was time frame reference. Nonetheless, all participants showed understanding of their role in relationships and exhibited concrete preferences. Our findings suggest that memory loss and other cognitive deficits associated with moderate to severe dementia do not necessarily lead to a loss of “self.”. (shrink)

We introduce the Vital Sign Ontology (VSO), an extension of the Ontology for General Medical Science (OGMS) that covers the consensus human vital signs: blood pressure, body temperature, respiratory rate, and pulse rate. VSO provides a controlled structured vocabulary for describing vital sign measurement data, the processes of measuring vital signs, and the anatomical entities participating in such measurements. VSO is implemented in OWL-DL and follows OBO Foundry guidelines and best practices. If properly developed and extended, we believe the VSO (...) will find applications for the EMR, clinical informatics, and medical device communities. (shrink)

Psychopathy refers to a range of complex behaviors and personality traits, including callousness and antisocial behavior, typically studied in criminal populations. Recent studies have used self-reports to examine psychopathic traits among noncriminal samples. The goal of the current study was to examine the underlying factor structure of the Self-Report of Psychopathy Scale–Short Form (SRP-SF) across complementary samples and examine the impact of gender on factor structure. We examined the structure of the SRP-SF among 2,554 young adults from three undergraduate samples (...) and a high-risk young adult sample. Using confirmatory factor analysis, a four-correlated factor model and a four-bifactor model showed good fit to the data. Evidence of weak invariance was found for both models across gender. These findings highlight that the SRP-SF is a useful measure of low-level psychopathic traits in noncriminal samples, although the underlying factor structure may not fully translate across men and women. (shrink)

Shortages of new therapeutics to treat coronavirus disease (COVID-19) have forced clinicians, public health officials, and health systems to grapple with difficult questions about how to fairly allocate potentially life-saving treatments when there are not enough for all patients in need (1). Shortages have occurred with remdesivir, tocilizumab, monoclonal antibodies, and the oral antiviral Paxlovid (2) -/- Ensuring equitable allocation is especially important in light of the disproportionate burden experienced during the COVID-19 pandemic by disadvantaged groups, including Black, Hispanic/Latino and (...) Indigenous communities, individuals with certain disabilities, and low-income persons. However, many health systems have resorted to first-come, first-served approaches to allocation, which tend to disadvantage individuals with barriers in access to care (3). There is mounting evidence of racial, ethnic, and socioeconomic disparities in access to medications for COVID-19 (4, 5). -/- One potential method to promote equitable allocation is to use a weighted lottery, which is an allocation strategy that gives all eligible patients a chance to receive the scarce treatment while also allowing the assignment of higher or lower chances according to other ethical considerations (6). We sought to assess the feasibility of implementing a weighted lottery to allocate scarce COVID-19 medications in a large U.S. health system and to determine whether the weighted lottery promotes equitable allocation. (shrink)

An often-overlooked characteristic of the human mind is its propensity to wander. Despite growing interest in the science of mind-wandering, most studies operationalize mind-wandering by its task-unrelated contents. But these contents may be orthogonal to the processes that determine how thoughts unfold over time, remaining stable or wandering from one topic to another. In this chapter, we emphasize the importance of incorporating such processes into current definitions of mind-wandering, and propose that mind-wandering and other forms of spontaneous thought (such as (...) dreaming and creativity) are mental states that arise and transition relatively freely due to an absence of constraints on cognition. We review existing psychological, philosophical and neuroscientific research on spontaneous thought through the lens of this framework, and call for additional research into the dynamic properties of the mind and brain. (shrink)

Context — Children and adults with psychopathic traits and conduct or oppositional defiant disorder demonstrate poor decision making and are impaired in reversal learning. However, the neural basis of this impairment has not previously been investigated. Furthermore, despite high comorbidity of psychopathic traits and attention deficit/hyperactivity disorder, to our knowledge, no research has attempted to distinguish neural correlates of childhood psychopathic traits and attention-deficit/hyperactivity disorder. Objective—To determine the neural regions that underlie the reversal learning impairments in children with psychopathic traits (...) plus conduct or oppositional defiant disorder. Design — Case-control study. Setting — Government clinical research institute. Participants — Forty-two adolescents aged 10 to 17 years: 14 with psychopathic traits and oppositional defiant disorder or conduct disorder, 14 with attention-deficit/hyperactivity disorder only, and 14 healthy controls. Main Outcome Measure — Blood oxygenation level–dependent signal as measured via functional magnetic resonance imaging during a probabilistic reversal task. Results — Children with psychopathic traits showed abnormal responses within the ventromedial prefrontal cortex (Brodmann area 10) during punished reversal errors compared with children wit hattention deficit/hyperactivity disorder and healthy children (P < .05 corrected for multiple comparisons). Conclusions — To our knowledge, this study provides the first evidence of abnormal ventromedial prefrontal cortex responsiveness in children with psychopathic traits and demonstrates this dysfunction was not attributable to comorbid attention-deficit/hyperactivity disorder. These findings suggest that reversal learning impairments in patients with developmental psychopathic traits relate to abnormal processing of reinforcement information. (shrink)

This chapter describes the potential far‐reaching consequences of contemplative higher education for the fields of science and medicine.